The A-NPs@(SHK+Ce6) nanosystem incorporates CaCO3 nanoparticles to buffer excess H+ ions and alleviate suppressive conditions, while the loaded SHK peptide inhibits lactate production and synergizes with photodynamic therapy to repolarize TAMs toward the M1 phenotype (53)
Song G, et al
For example, N-acetylcysteine (NAC), a potent antioxidant, has been examined in clinical trials of NPC disease, which shows increased oxidative stress and dysfunctional autophagy (Wheeler and Sillence, 2020)
Under conditions of oxidant attack, GSH is rapidly converted to GSSG, making the elevation of the intracellular GSSG/GSH ratio a widely accepted marker for oxidative stress
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DED is categorized into two primary categories such as aqueous-deficient dry eye and evaporative dry eye