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64 Additionally, SIRT2 exerts an inhibitory effect on adipogenesis by FOXO1 deacetylation and subsequent PPAR transcriptional activity repression
Qin Y, et al
A test involving 164 men who followed the protocol for six monthsdetails published in June 2026reported zero measurable change in body weight, waist circumference, or self-reported appetite compared to a baseline control period
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Peleg et al., 2016
To put that in perspective, a 200-pound person could expect to lose 30 to 40 pounds
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