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doi: 10.3389/fendo.2014.00056 Received 20 March 2014 Accepted 07 April 2014 Published 22 April 2014 Volume 5 - 2014 Edited by Rosaria Meccariello, University of Naples Parthenope, Italy Reviewed by Rosanna Chianese, Second University of Naples, Italy

pylori infection, as well as to the chronic use of over-the-counter nonsteroidal anti-inflammatory drugs, such as aspirin and ibuprofen (Motrin, Advil)