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Reconstitution introduces another variable: lyophilized peptides must be mixed with bacteriostatic water and dosed accurately, where small volume errors translate into large dose errors
These are separate issues that require separate analysis
Truth: this is likely truewith a caveat
and this is a good segway into our next section
This pattern is closer to the Phase 2 trial design (continuous across 48 weeks) than the 8-on / 8-off cyclical pattern
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