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Their use in clinical practice is considered off-label, based on emerging research, clinical experience, and patient-specific therapeutic goals
It can make you feel irritable and tired
Understanding the trajectory helps frame current purchasing decisions in proper context
A few people reported that they had not noticed any improvement in their skin after using it for 2 weeks to a month
Even after eventual FDA approval, coverage is not guaranteed, as many insurance plans exclude weight loss medications
With no head-to-head study, comparing the two requires stitching together trials that differ in population, comparator, endpoint, and duration a chain with several weak links
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