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In a 2025 Reuters report, several digital health startups admitted to using anonymized patient data to optimize marketing performance - a practice technically legal but ethically murky when linked to medical outcomes

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An important limitation of the DSIP literature is that much of the human research was published decades ago, primarily during the 1980s and early 1990s

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Using this invasive technique, intra-arterial infusion of lipoic acid was found to improve endothelium-dependent vasodilation in 39 subjects with type 2 diabetes but not in 11 healthy controls (62)

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