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The results can be unpredictable and the procedure can lead to severe side-effects

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This guide walks through the clinical landscape of compounded HRT prescribingfrom when compounding is clinically appropriate, to the formulations and dosage forms available, to how prescribers can select quality compounding partners and streamline the ordering process

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doi:10.1093/ajcn/87.2.362

No trial was designed to compare the two as monotherapies, so better cannot be established head-to-head