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An infant might only be able to safely fast for 3-4 hours, while a treated adult might be cleared to fast for 8-10 hours overnight

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That means portioning for your real appetite, not your ideal one

That may include weight loss, improved insulin sensitivity, reduced visceral fat, better cardiometabolic markers, lower inflammatory burden, improved mobility, and greater capacity to exercise

The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling

FDA labeling includes a boxed warning regarding thyroid C-cell tumors based on rodent studies, though human relevance remains uncertain