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Weight regain is common after cessation of pharmacotherapy
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The sequence used a 2x-150-bp paired-end (PE) configuration
In terms of receptor activation, chlordane+PCB126 activated hepatic xenobiotic receptors, namely CAR ( Cyp1b10 ) and AHR ( Cyp1a2 ) but PXR ( Cyp3a11 ) was activated only in males, implicating how sex+HFD interactions impact these receptors as potential drivers of toxicant-induced hepatic metabolic disruption and possibly injury
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