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[Source: Fierce Pharma ] January 2025 The FDA fast-tracked tirzepatide for cardiovascular risk reduction in obesity patients, following landmark trial results showing significant benefit beyond weight loss

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GSEA analysis revealed a significant enrichment of a NRF2 stress-response signature 31

Parallel fibrogenesis in the liver and myocardium adds to ventricular stiffness and diastolic dysfunction, while gut dysbiosis from a Western diet heightens systemic inflammation and endotoxemia, worsening cardiac and hepatic dysfunction

GLP-1MK-801 was incubated in PBS with 200 mM glutathione at pH 7.0

We havent had a medicine to deal with a problem this big and with such significantly positive results maybe ever