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There is no universal timeline because different peptides serve different purposes
Under normal conditions, TFEB is phosphorylated by mTORC1 and exists mainly in an inactive state in the cytosol (Martina and Puertollano, 2013)
Aging may be defined as a progressive and general decrease of the organism functions that leads to a lower ability to adaptively react to changes and preserve homeostasis
Samulak JJ, Sawicka AK, Samborowska E, Olek RA
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