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Side Effect 1: Injection Site Reactions The most common side effects occur at the injection site, including pain, redness, and mild swelling

Future research should focus on personalized therapeutic interventions based on the dominant molecular perturbations in individual patients

Kruljac I, Miroevi G, Kirigin LS, et al

Phase 2 clinical trial data published in the New England Journal of Medicine (Jastreboff et al., 2023) demonstrated mean body weight reductions of up to approximately 24% over 48 weeks in adults with obesity a notable finding, though long-term durability data and head-to-head comparisons with other treatments are not yet available

Such data are essential to guide evidence-based, multidisciplinary perioperative management strategies.