The STEP (Semaglutide Treatment Effect in People with obesity) trial program showed average weight reductions of approximately 15% of initial body weight over 68 weeks in individuals without diabetes, with somewhat lower reductions (about 9-10%) in those with type 2 diabetes
For many patients, paying $349 monthly is simpler and faster than navigating assistance applications, even if they might qualify for free medication
People taking semaglutide who also consume alcohol should be particularly vigilant about this, as alcohol is an independent risk factor for pancreatitis that can compound any GLP-1-related risk
MNT spoke with Jeffrey Zarin, MD, an orthopedic surgeon specializing in joint replacement surgery at Cedars-Sinai Orthopaedics in Los Angeles, CA, about this study, who commented that his first reaction was to be cautious about over-interpreting its findings
Localization and Effect of Ectopic Expression of CPT1c in CNS Feeding Centers
Dietary Carbohydrate (Amount and Type) in the Prevention and Management of Diabetes: A statement by the American Diabetes Association