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They do this in several ways: They boost insulin release when blood sugar rises They reduce glucagon (a hormone that increases blood sugar) They slow down stomach emptying, which prevents blood sugar spikes after meals For people with type 2 diabetes, these effects can mean better control of blood sugar levels and lower A1C (a measure of average blood sugar over time)
Conclusion Clinical trials show that GLP1 medications can produce meaningful weight loss, averaging 10 to 22% of body weight depending on the medication and dose
Archived from the original on 9 November 2010
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Obesity is a chronic condition, and patients may benefit from taking GLP-1s long term, especially if they also have conditions such as diabetes, cardiovascular disease, obstructive sleep apnea, or metabolic dysfunction-associated steatohepatitis (MASH)
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