This GLP-1R-mediated modulation of transport activity likely represents the molecular coupling between GLP-1R inhibition and the observed Ex9-39-induced reduction in CSF secretion, via reduced cAMP-dependent protein kinase A-mediated phosphorylation of NKCC1 and the Na + /K + -ATPase, and thus lowered activity of these proteins [51,52,53]
Small Maf functions in the maintenance of germline stem cells in the Drosophila testis
Animal and laboratory studies suggest that IGF-1 signalling may enhance the healing response following connective tissue injury
Cell 167:843857.e814 Ethics declarations Funding This work was supported in part by Deutsches Zentrum fr Diabetesforschung (DZD), Alexander von Humboldt Foundation, Helmholtz Alliance ICEMED through the Initiative and Networking Fund of the Helmholtz Association, and the Helmholtz cross-program topic Metabolic Dysfunction
doi:10.1007/s12264-013-1424-x 153
None of them is active at MC2R, the adrenocorticotropin receptor