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Thymic stromal lymphopoietin receptor-mediated il-6 and cc/cxc chemokines expression in human airway smooth muscle cells: role of mapks (Erk1/2, P38, and jnk) and stat3 pathways

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Mattanovich D, Sauer M, Gasser B

Despite this, a substantial body of pre-clinical and limited clinical research has mapped DSIPs pharmacological effects across multiple systems, identifying several probable mechanistic axes including NMDA receptor modulation, adrenergic system regulation, MAPK/ERK cascade interaction, and mitochondrial respiration effects while acknowledging that the existence of an undiscovered DSIP-like endogenous peptide(s) may account for part of the DSIP-like immunoreactivity observed in tissue distribution studies

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