Effects of gestational and lactational exposure to coplanar polychlorinated biphenyl (PCB) congeners or 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) on thyroid hormone concentrations in weanling rats
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It is postulated that through these mechanisms, NAD+ repletion might improve cellular energy capacity and resistance to oxidative stress
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In contrast, GSH depletion drives M1 polarization, resulting in heightened secretion of pro-inflammatory cytokines, including TNF-, IL-6, and IL-1 (Kwon et al., 2019)