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In this Review, we synthesize the current mechanistic understanding of SGLT2 inhibitors and highlight key directions for the future of cardiovascularkidneymetabolic disease management

Diz JBM, Queiroz BZD, Tavares LB, Pereira LSM

There is science and its applications, which are related to one another as the fruit is related to the tree that has borne it." It's very hard to predict the usefulness of knowledge that seems useless today

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doi: 10.1007/s12020-014-0361-4 13 ChengLHuYLiYYCaoXBaiNLuTTet al

Inhibition of DPP-IV activity in wild-type mice by pharmacological agents results in improvement in glucose tolerance, whereas this effect has not been observed in DPP-IV knockout mice (Marguet et al