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Ships within 48 hours · Estimated delivery Oct 3 - Oct 8
For short-term storage, standard refrigeration (2C to 8C) is acceptable
TB-500's parent compound (Thymosin Beta-4) has more human clinical exposure through RegeneRx trials
Gu S, Shi J, Tang Z, et al
Methionine and methionine sulfoxide treatment induces M1/classical macrophage polarization and modulates oxidative stress and purinergic signaling parameters
sgRNA constructs and gene expressing codon optimized (OPT) plasmid constructs sgRNA control and constructs against CBS and L2HGDH were designed targeting GTATTACTGATATTGGTGGG (sgControl) (#230080, Addgene), GGAGCAGACAACCTACGAGG (sg CBS -1) (#230081, Addgene), TGGCAGTGCTGGCAGCACGG (sg CBS -2) (#230082, Addgene), GATATAGTCATCGTTGGTGG (sg L2HGDH -1) (#230083, Addgene), and CACCAGACTGGACATAACAG (sg L2HGDH -2) (#230084, Addgene) and constructed in lentiCRISPR v2-Blast (#83480, Addgene) for Blasticidin selection at a final concentration of 5 g/ml
XIAP-ULK1-mediated mitophagy modulates carnitine metabolism to mitigate diabetic kidney disease
