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3.1 Bacterial Pathways Directly Implicated in Levodopa Metabolism Levodopa, the mainstream treatment for PD, is a non-proteogenic large neutral amino acid (LNAA) produced by the hydroxylation at the meta-position of the phenyl ring of tyrosine [30]

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tirzepatide lowered HbA 1c by 2.01 to 2.30 percentage points versus 1.86 for semaglutide, meeting non-inferiority and superiority, with greater weight loss as well