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Sources Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: The SURMOUNT-4 Randomized Clinical Trial (2024) Journal of the American Medical Association [Accessed 2 December 2025] Dosing Schedule | Ozempic (semaglutide) (2025) [Accessed 2 December 2025] GIP and GLP1, the two incretin hormones: Similarities and differences (2010) Journal of Diabetes Investigation [Accessed 2 December 2025] Once-Weekly Semaglutide in Adults with Overweight or Obesity (2021) New England Journal of Medicine [Accessed 2 December 2025]

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While not all side effects can be avoided, many people find that small changes help reduce how intense symptoms feel