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"Obesity is caused by an energy imbalance, with more calories being consumed than are burned

Case 1 A 46-year-old female with history of rheumatoid arthritis and overweight (BMI of 35) currently on methotrexate (for total of 3 years) and semaglutide for weight loss (0.5 mg/subcutaneous weekly injection for total of 12 weeks) presented to the oral medicine clinic

It works by influencing gut hormones, including GLP-1, to improve satiety and energy balance

The hypothalamus represents a primary site of GLP-1 action, particularly in areas regulating energy homeostasis and appetite

For instance, some telehealth programs may offer lower out-of-pocket pricing through membership models or by helping patients access manufacturer or pharmacy savings programs

OConnor 2025)