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Crucially, only 37% of all pivotal trials in that decade even reported ethnicity data at all, and sex representation skewed in the opposite direction from race, with women under-represented by 7.3 percentage points and men over-represented by 7.5 percentage points ( [96] )

BuscemiNVandermeerBHootonNPandyaRTjosvoldLHartlingLet alEfficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: meta-analysis

They may include symptoms beyond breakouts

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