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This observation has driven a long history of research into precursor approaches
62 Example: enfuvirtide (Fuzeon)
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These animals failed to grow normally, developed cataracts, exhibited increased levels of oxidative DNA damage, and were prone to developing oxygen-induced lung injury and died prematurely owing to cysteine deficiency, reduced intracellular GSH, and increased oxidative stress [9,19]
The rates of AF over the 2-year study period were similar between patients receiving the drug and those receiving the placebo
one included an additional 1 mg arm [25], two had two arms of 10 and 15 mg [27,29], and one trial administered a single tirzepatide arm at the maximum tolerated dose (either 10 or 15 mg) [28]
