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However, these guidelines largely focused on hydrochlorothiazide, not chlorthalidone or other thiazide-like drugs like indapamide (Stafford et al., 2010

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Functional gastrointestinal disorders: history, pathophysiology, clinical features, and Rome IV

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Serious risks are uncommon but include pancreatitis, gallbladder disease, acute kidney injury from severe dehydration, and worsening diabetic retinopathy in susceptible patients

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The evidence supports their safety in psychiatric populations

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