Using structure-based analyses and cell models, including patient fibroblasts, of this variant, we found that the missense variant destabilized a critical loop, which disrupted the active site and caused a substantial loss of enzymatic function
Ghosh A, Pareek A, Sopory SK, Singla-Pareek SL (2014) A glutathione responsive rice glyoxalase II, OsGLYII-2, functions in salinity adaptation by maintaining better photosynthesis efficiency and anti-oxidant pool
Reduce mucosal protection in the stomach 9
Genetic inactivation of the sigma-1 chaperone protein results in decreased expression of the R2 subunit of the GABA-B receptor and increased susceptibility to seizures
Its high chlorophyll content also aids in detoxification
Your body naturally produces thousands of them, and they act as chemical messengers, helping cells communicate and directing everything from hunger and metabolism to sleep, mood, and recovery