Glucagon receptor agonism stimulates hepatic glucose production, increases lipolysis (fat breakdown), promotes fatty acid oxidation in the liver, and elevates resting metabolic rate through thermogenesis
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For patients whose levels fall in the borderline or gray zone, a methylmalonic acid (MMA) test provides greater specificity MMA levels rise when B12 is functionally inadequate at the cellular level, even if serum B12 appears borderline normal
2026 Weight Loss Medication Timeline: Key FDA Decisions, GLP-1 Drug Launches, and What to Expect The weight loss medication market is changing rapidly as new GLP-1 drugs reach regulatory milestones
Diabetes Epidemiology and Management 14: 100209