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Electron microscopy, the sole method capable of ascertaining the presence of a synaptic contact, defines a synapse by a presynaptic compartment containing small-diameter secretory vesicles juxtaposed to a postsynaptic electron-dense zone 46
Tirzepatide may cause slightly more headaches initially due to its dual receptor activation affecting both GLP-1 and GIP pathways in the brain simultaneously, though the data does not show a statistically significant difference between the two medications
The duration of therapy is not specified, although most studies have recommended 12 weeks to obtain results
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