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Ruzieh M, Batizy L, Dasa O, Oostra C, Grubb B

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This regional selectivity makes the peptide valuable for addressing stubborn fat accumulation, particularly in the midsection

based on consistent formation of -helical structure in initial rounds of structure calculations in which no hydrogen bond restraints were defined), inter-molecular PRE restraints (4 non-interacting copies of the spin label to account for different spin label orientations), inter- and intra-molecular NOE restraints, and ambiguous distance restraints for residues showing CSPs upon binding