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In pernicious anaemia, the immune system mistakenly attacks the gastric parietal cells that produce intrinsic factor, leading to B12 deficiency over time
Thus, the neuroprotective effects exhibited by curcumin in preclinical TBI models can be attributed to its ability to modulate oxidative stress, neuroinflammation, mitochondrial dysfunction, and autophagy
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Cells then recycle it back using an enzyme (glutathione reductase), creating a powerful protection cycle
10.1016/j.regpep.2009.11.005 20 GojkovicS.KrezicI.VrdoljakB.MalekinusicD.BarisicI.PetrovicA.et al (2020)
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