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It was therefore concluded that NiCl 2 induces p38 MAPK-dependent lytic cell death and stimulates markers of premature eryptosis, which may explain the changes in hematological parameters observed in poisoning victims [420]
Comparative mechanistic study of RPE cell death induced by different oxidative stresses
Amasi-Hartoonian N, et al
however, in addition to its antioxidant effect, it also promotes prooxidant behavior
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