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The most common adverse events are gastrointestinal: nausea (occurring in 12-33% of subjects depending on dose), diarrhea, constipation, and decreased appetite
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(April 14, 2005)
An increase in the Akkermansia spp population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice (in Eng)
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Strict vegetarians and vegans are at high risk for developing a B12 deficiency if they dont eat grains that have been fortified with the vitamin or take a vitamin supplement
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