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GLP-1 medications that have been frozen should be discarded immediately and not used, even after thawing
Whilst early Phase 2 data suggest favourable effects on blood pressure and lipid profiles, the drug has also been associated with dose-dependent increases in resting heart rate
Y.ChenF
doi: 10.3389/fendo.2023.1214334
However, it remains unclear whether lowering Lp(a) levels translates into fewer heart attacks and strokes and large-scale clinical trials are underway to answer that question
The increase from 10 mg to 15 mg yields more modest incremental benefit
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