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Nausea, vomiting, diarrhea, and constipation were the most common gastrointestinal adverse effects

Clinical trials have documented that patients who lose more than 20% of their body weight are at higher risk for hair shedding

Patients with a BMI of 30 and greater, along with obese patients suffering from related healthcare issues with a BMI of 27 are generally approved for this weight loss therapy

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This creates a self-reinforcing cycle: low testosterone promotes further fat accumulation, which drives more aromatase conversion, leading to even lower testosterone (Cohen, 1999, Journal of Clinical Endocrinology & Metabolism )

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