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Ashrafizadeh, M
Pentadecapeptide BPC-157 enhances the growth hormone receptor expression in tendon fibroblasts
The peptide sequence, alanine-histidine-lysine bound to copper, was chosen because of how it interacts with growth factor receptors and anti-apoptotic pathways
In addition, there are polar regions composed of the following residues: H335, T378, Q450, N590, Q1239, T1241, and T1242
Instead, healing produces fibrotic scar tissue with altered collagen organization and inferior mechanical properties compared with healthy tendon
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