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Circulating GLP-1 exists only at low picomolar concentrations, is rapidly inactivated by DPP-4 enzymes and is swiftly cleared by the kidneys (Hansen et al., 1999
The studies by Anholm C, et al
The manufacturers of these drugs have priced them at more than $1,000 per month, and limited competition in the space is putting them out of reach for many patients and creating financial burden on healthcare systems
For the full pharmacology profile, visit the tirzepatide peptide page
For people with type 2 diabetes and early-stage kidney problems, this treatment could offer a better way to protect kidney function and improve overall health
