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The IF group showed significant decreases in serum malondialdehyde (MDA) levels ( P = 0.02) and neutrophil-to-lymphocyte ratio ( P = 0.018) and increased catalase levels ( P = 0.004) compared to the control group

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Note: All cited research relates to in-vitro, animal model, and observational/mechanistic human studies

The pathogenesis of RIP involves multiple pathological processes, including radiation-induced excessive production of reactive oxygen species (ROS), leading to oxidative stress, which in turn triggers apoptosis and mucosal barrier disruption, as well as an inflammatory cascade centered on proinflammatory cytokines