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The mechanism behind GLP-1 medications involves their interaction with the gastrointestinal tract, where they can alter motility and affect how quickly food moves through the digestive system

Patients with significant gastroparesis, history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, or pancreatitis warrant particular care with the GLP-1 component, regardless of the AOD-9604 question

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doi :10.1515/BC.2009.033 Allen J, Bradley RD

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Various NOX isoforms (e.g., NOX2, NOX4) are expressed in cardiomyocytes, endothelial cells, and fibroblasts