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For the immunohistochemical technique, 3 m sections were done of each selected paraffin block, using the Envision System (Dako, USA), following standardized protocol with adequate controls and using the following antibodies: S100 protein, HMB45, Neuron specific enolase (NSE), Cytokeratin AE1-AE3 (CKAE1-AE3), (GFAP), chromogranin, synaptophysin and p53

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doi:10.1016/j.maturitas.2016.04.006 Moscatelli F, Monda A, Messina G, et al

Diabetes Obesity Metab 22:335345 Awad A, Madla CM, Mccoubrey LE, Ferraro F, Gavins FK, Buanz A, Gaisford S, Orlu M, Siepmann F, Siepmann J (2022) Clinical translation of advanced colonic drug delivery technologies

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Here's what we've learned from supporting 37+ GLP-1 programs: #ClinicalTrials #Obesity #PatientEngagement #GLP1 #ClinicalOperations GLP-1 RAs in Obesity Trials: Addressing Dropout Rates GLP-1 receptor agonists (GLP-1 RAs) are transforming obesity treatment, but the trials designed to evaluate them are losing participants before the finish line