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This rapid effect on vessel structure occurs before gene expression changes fully manifest, suggesting direct molecular interactions alongside the longer-term transcriptional effects

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The real-world analysis evaluated adults treated between May 2022 and September 2023 and found that patients receiving tirzepatide were more likely to achieve clinically meaningful weight loss and experienced larger reductions in body weight at 3, 6, and 12 months of treatment

Karen Kaufman, board certified OB/GYN