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At 48 weeks: 8.7% with 1 mg 17.1% with 4 mg 22.8% with 8 mg 24.2% with 12 mg Compared to just 2.1% with placebo

Constipation is listed among common gastrointestinal adverse reactions with semaglutide, the GLP-1 receptor agonist used in Wegovy

To the point where, as an obesity medicine specialist, I rarely prescribe metformin as an anti-obesity medication unless there are compelling reasons against using other anti-obesity medications. He does, however, prescribe it to prevent weight gain from certain conditions or medications for which putting on pounds is a common side effect

T., Fakhoury, J

There are no specific characteristics that increase the risk of a person getting drug-induced hyperhidrosis

Beyond just sticker price, theres also the question of administration: swallowing a tablet is a lot less hassle than injecting a weekly shot, and that convenience has its own value