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Hydrophobic contacts specifically contribute to peptide binding at the neuropeptide Y2 receptor

Tirzepatide regulates blood sugar, makes you feel full for longer, controls feelings of hunger and craving in the brain, and helps regulate fat cells and adiposity

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Participants on Zepbound also experienced substantial weight loss -- averaging 18% to 20% of their body weight (approximately 45 to 50 pounds) over the course of a year -- compared to 1.6% to 2.3% for those on placebo

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