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The use of RIPK1 inhibitor (Necrostatin-1) [238] combined with NAC can block oxidative stress by reducing H 2 O 2 /O/OH/LOOH, therefore significantly decreasing myocardial cell damage and improving cardiac function [239]

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IF and Cardiac Physiology Cardiovascular diseases (CVD) are a leading cause of global mortality, accounting for approximately one-third of all deaths worldwide [76]

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