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Human clinical data does not exist

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Oxidative stress is an imbalance between oxidants and antioxidants in favor of the oxidants, leading to a disruption of redox signaling and control and/or molecular damage (Sies, 2015) that harm lipids, proteins and DNA (Schieber and Chandel, 2014)

Xu J, Yuan C, Wang G, Luo J, Ma H, Xu L et al (2018) Urolithins attenuate LPS-induced neuroinflammation in BV2 microglia via MAPK, Akt, and NF-B signaling pathways

Tesamorelin is an FDA-approved treatment for reducing excess abdominal fat in HIV-infected patients with lipodystrophy and may be administered as a standalone treatment

Heat stress in plants: sensing, signalling and ferroptosis