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240 In glioblastoma, hepatocyte growth factor (HGF)/c-Met signaling enhances -catenin nuclear localization and LEF1-dependent transcription of MDRassociated genes such as MRP-1, inducing CSC traits, endothelialmesenchymal transition (EndMT), and temozolomide resistance

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Failure of DNA repair induces apoptosis through p53 activation, mitochondrial pathway induction, and persistent DNA damage response (DDR) signaling 8-10

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In fact, Glutathione is found in every cell in the body and is essential for healthy immune function, detoxification, and the maintenance of healthy skin