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A recent study published in The New England Journal of Medicine furthered research on semaglutide, exploring how the drug affected outcomes for people with metabolic dysfunction-associated steatohepatitis, a type of liver disease

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Mean body weights decreases of 12.7% over placebo were seen after 68 weeks in Rybelsus treated patients

GLP-1 helps regulate blood sugar by stimulating insulin release and suppressing glucagon, a hormone that raises blood sugar

For example, certain GLP1R variants correlate with stronger appetite signaling rebound, suggesting benefit from slower tapering schedules