The mechanism involves upregulation of growth hormone receptors in tendon fibroblasts and increased collagen synthesis at the repair site
Cell Res 403 , 112615 (2021)
What the FDA says (and does not say) As of early 2026, the FDA-approved prescribing information for Ozempic (semaglutide for diabetes) and Wegovy (semaglutide for weight loss) does not list blood clots, DVT, or VTE as known side effects or warnings
Pautler approaches these procedures thoughtfully and strategically, often combining surgeries in ways that reduce operating time, minimize blood loss, and limit the number of recoveries a patient has to go through
In clinical trials: About 5% of people taking Ozempic reported constipation About 24% of people taking Wegovy reported constipation GLP-1 medications can slow digestion and reduce how often you go, especially in people with a higher body weight
Metformin carries a boxed warning for lactic acidosis a rare but life-threatening condition caused by a buildup of lactic acid in the blood