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Baseline Risk Assessment : Before initiating GLP-1 therapy, clinicians should evaluate baseline fracture risk using established tools such as the FRAX (Fracture Risk Assessment Tool) calculator, which incorporates age, sex, body mass index, prior fractures, family history, and other clinical risk factors
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Important Safety Information Warning: Risk of Thyroid C-Cell Tumors In rat studies, semaglutide caused thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in a dose- and duration-dependent manner
People prescribed semaglutide often have more advanced diabetes, higher body mass index, or additional vascular risk factors that independently increase the likelihood of NAION
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