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The blocking of the lysosomal iron translocation of CSCs by inhibiting the divalent metal transporter 1 (DMT1) leads to iron accumulation and cell death with features of ferroptosis (Turcu et al., 2020)

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There was no significant difference in the incidence of adverse events and serious adverse events in patients with diabetic neuropathy who took 600 mg/day of lipoic acid for four years compared to those in the placebo group (78)

Effective, but expensive and less stable

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(2022) found that QCN improves mitochondrial biogenesis by reducing the generation of ROS in neuronal SH-SY5Y cells