Start with a dose of 3 mg daily
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adults who are overweight and have a weight-related medical problem (e.g., blood pressure, type 2 diabetes, or high cholesterol) To reduce the risk of major adverse CV events in: adults with established cardiovascular disease who have obesity or are overweight
Current-clamp recordings illustrated that exendin-4 induces a small reduction in evoked action potential from medium spiny neurons (MSNs) suggesting slightly postsynaptic effects
doi:10.1016/j.eclinm.2024.102624 Palermo A, DOnofrio L, Eastell R, Schwartz AV, Pozzilli P, Napoli N